[儿童慢性铅中毒：临床经验]

[Chronic lead poisoning in childhood: clinical experience].

作者信息

Carnelli V, Ronco G, Farolfi A, Simoni L, Siccardo L, Biella C A, Giulotto P

出版信息

Pediatr Med Chir. 1984 May-Jun;6(3):377-82.

Abstract

Since 1978, 818 children living near an industrial source of pollution have been screened for lead poisoning. Biochemical evidences of increased lead absorption have been found in 114 cases and in 62 of them it was of such degree to guarantee further investigations. Those 62 children received a thorough neuropsychologic evaluation revealing a significant reduction of IQ, learning difficulties, poor concentration and behavioral abnormalities. We also documented an increased rate of abnormal mathafases and breaks of chromatides in children with increased lead absorption compared with age and sex matched controls.

摘要

自1978年以来，对居住在工业污染源附近的818名儿童进行了铅中毒筛查。在114例中发现了铅吸收增加的生化证据，其中62例的铅吸收程度足以保证进一步调查。这62名儿童接受了全面的神经心理学评估，结果显示智商显著降低、学习困难、注意力不集中和行为异常。我们还记录到，与年龄和性别匹配的对照组相比，铅吸收增加的儿童中，异常有丝分裂和染色单体断裂的发生率更高。