头孢噻吩在治疗细菌性心内膜炎期间引起了中性粒细胞减少。
Cephalothin induced neutropenia during the treatment of bacterial endocarditis.
作者信息
Holt S, Khan M M, Orlans D A, Epstein E J
出版信息
Scott Med J. 1978 Apr;23(2):135-9. doi: 10.1177/003693307802300207.
PMID:644296
Abstract
The occurrence of cephalothin induced neutropenia in 3 patients with infective endocarditis is described. In each patient, withdrawal of cephalothin was followed by rapid haematological recovery. It is apparent that granulocytopenia may frequently occur in patients receiving prolonged, high dose, intravenous cephalothin for the treatment of bacterial endocarditis.
摘要
本文描述了3例感染性心内膜炎患者发生头孢噻吩诱导的中性粒细胞减少症的情况。在每例患者中，停用头孢噻吩后血液学迅速恢复。显然，在接受长期、高剂量静脉注射头孢噻吩治疗细菌性心内膜炎的患者中，粒细胞减少症可能经常发生。
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