Rodger R S, Fletcher K, Dewar J H, Genner D, McHugh M, Wilkinson R, Ward M K, Kerr D N
Uremia Invest. 1984;8(2):89-96. doi: 10.3109/08860228409080989.
In a study of dialysis patients 79% of men complained of sexual dysfunction and 61% erectile impotence following uremia and the onset of regular dialysis therapy. Plasma testosterone levels were significantly higher in patients treated by continuous ambulatory peritoneal dialysis (p = 0.001) but the incidence of sexual dysfunction was not different from patients treated by hemodialysis. Although follicle-stimulating hormone levels were higher (p = 0.001) and penile blood pressure index levels lower (p less than 0.05) in patients with impotence, sexual function was not improved by exogenous testosterone, and vasculogenic impotence was identified in only 6% of patients. These findings suggest that a major component of uremic impotence is unrelated to primary testicular failure or penile vascular insufficiency.
在一项针对透析患者的研究中，79%的男性在患尿毒症并开始定期透析治疗后出现性功能障碍，61%出现勃起功能障碍。持续非卧床腹膜透析治疗的患者血浆睾酮水平显著更高（p = 0.001），但性功能障碍的发生率与血液透析治疗的患者并无差异。尽管阳痿患者的促卵泡激素水平更高（p = 0.001）且阴茎血压指数水平更低（p < 0.05），但外源性睾酮并不能改善性功能，且仅6%的患者被诊断为血管性阳痿。这些发现表明，尿毒症性阳痿的主要原因与原发性睾丸功能衰竭或阴茎血管功能不全无关。
