铜绿假单胞菌。一、用于疫苗接种目的的生产菌株的大规模培养。
Pseudomonas aeruginosa. I. Large-volume cultivation of production strains for vaccination purposes.
作者信息
Bĕlohlávek S, Pavlík V, Rencová J, Benácková E, Stránský V, Sourek J, Výmola F
出版信息
J Hyg Epidemiol Microbiol Immunol. 1984;29(3):297-302.
PMID:6443364
Abstract
A submerged culture technology was used to produce large-volume suspensions of Pseudomonas aeruginosa production strain for the purpose of vaccination. This paper describes the composition of the culture media used and the methods of preparing endotoxin and exotoxin components of the desired immunogenic activity.
摘要
为了疫苗接种的目的，采用深层培养技术来生产大量铜绿假单胞菌生产菌株的悬浮液。本文描述了所用培养基的组成以及制备具有所需免疫原活性的内毒素和外毒素成分的方法。
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