Fitzcharles M A, Benatar S R
S Afr Med J. 1978 Jan 14;53(2):63-6.
A patient with Goodpasture's syndrome who presented with severe pulmonary haemorrhage and minimal renal involvement is described. The diagnosis was substantiated by immunofluorescence studies on a renal biopsy specimen and by the detection of circulating antiglomerular basement membrane antibody. The patient was treated with corticosteroids and cyclophosphamide. He remains in good health 20 months after diagnosis, although there is a persisting abnormality in single-breath gas transfer for carbon monoxide. Recovery from Goodpasture's syndrome is reviewed in the light of recent advances.
本文描述了一名患有Goodpasture综合征的患者，该患者表现为严重肺出血且肾脏受累轻微。通过对肾活检标本进行免疫荧光研究以及检测循环抗肾小球基底膜抗体，证实了诊断。患者接受了皮质类固醇和环磷酰胺治疗。诊断后20个月，他仍健康状况良好，尽管单次呼吸一氧化碳气体交换仍存在持续异常。根据最新进展对Goodpasture综合征的康复情况进行了综述。
