Hinman A R, Jordan W S
Public Health Rep. 1983 Sep-Oct;98(5):436-43.
Dramatic progress has been made in reducing morbidity due to infectious diseases of childhood through programs of universal immunization of children. This success has been achieved by a program that involves a remarkable integration of private and public endeavors and cooperation between official and voluntary agencies. Similar models of cooperation and integration have not yet been developed for selective use vaccines and new vaccines. As a consequence, although it seems likely that the childhood immunization objectives will be achieved by 1990, the ability to achieve objectives for selective use and new vaccines is in doubt. The National Institute of Allergy and Infectious Diseases has undertaken, as an initiative, the accelerated development of new vaccines. The goal is to expedite the availability of needed vaccines by selecting a few candidate vaccines for extra research and development efforts. Studies are in progress on more than 50 antigens for more than 30 different bacterial, viral, and parasitic diseases.
通过儿童普遍免疫计划，在降低儿童传染病发病率方面已取得显著进展。这一成功是通过一个涉及私营和公共部门显著整合以及官方与志愿机构合作的计划实现的。对于选择性使用疫苗和新疫苗，尚未开发出类似的合作与整合模式。因此，尽管到1990年似乎有可能实现儿童免疫目标，但实现选择性使用和新疫苗目标的能力仍存在疑问。作为一项举措，国家过敏和传染病研究所已着手加速新疫苗的研发。目标是通过挑选几种候选疫苗进行额外的研发工作，加快所需疫苗的供应。目前正在对30多种不同细菌、病毒和寄生虫疾病的50多种抗原进行研究。
