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血管外压力对静脉压升高引起的小肠血管阻力变化的影响。

Influence of extravascular pressure on changes induced in vascular resistance in the small intestine by elevated venous pressure.

作者信息

Török J

出版信息

Physiol Bohemoslov. 1980;29(1):63-71.

PMID:6444740
Abstract

The influence of the extravascular pressure on the size of the increase in vascular resistance after elevation of venous outflow pressure (venous-vasomotor response) was studied in an intestinal segment, perfused at a constant rate, in anaesthetized dogs. If pressure in the lumen of the intestine was elevated (spontaneously, pharmacologically, mechanically) or pressure in the plethysmograph was raised, venous-vasomotor responses were either smaller or absent. When pressure in the intestinal lumen was raised, blood volume increments produced in the segment by elevated venous pressure were significantly smaller than those observed in the presence of resting pressure. The presence of a venous-vasomotor response was correlated to the quantitative relationship between the extravascular and the venous pressure. Its induction was dependent on whether the outflow venous pressure was higher than the pressure values in the intestinal lumen or the plethysmograph; in that case it developed to an extent corresponding to the increment in transmural vascular pressure.

摘要

在麻醉犬身上,对一段以恒定速率灌注的肠段进行研究,探讨血管外压力对静脉流出压升高后血管阻力增加幅度(静脉血管运动反应)的影响。如果肠腔内压力升高(自发地、通过药物或机械方式)或体积描记器内压力升高,静脉血管运动反应要么较小,要么不存在。当肠腔内压力升高时,静脉压升高在该段产生的血容量增加明显小于在静息压力下观察到的情况。静脉血管运动反应的存在与血管外压力和静脉压力之间的定量关系相关。其诱发取决于流出静脉压是否高于肠腔或体积描记器中的压力值;在这种情况下,它会发展到与跨壁血管压力增量相对应的程度。

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