Bias K
Fortschr Med. 1980 Jan 24;98(3):108-10.
Actovegin can be stated to represent a genuine acquisition to the therapy of acne vulgaris. Considering both the parenteral and oral treatment as an entity, complete cure was achieved in 54 out of a total of 88 patients. An improvement was obtained in 28 patients, so that further treatment was no longer required because a few acne pimples only occurred premenstrually. Improvement was in fact likewise obtained in 6 cases, but acne was seen to recur after discontinuation of therapy so that maintenance treatment had to be carried out. On dividing the mode of treatment into parenteral and oral treatment groups, the result distinctly suggests that parenteral treatment is better. The parenteral treatment was shown to be 50 per cent superior to the oral form. I deem it appropriate to initiate the treatment of any form of acne by a course of injections and, depending on the success seen, to change over to oral treatment. In any case, the dosage of both parenteral and oral therapy will have to be adjusted individually. (Chart: see text)
爱维治可以说是寻常痤疮治疗方面的一项真正收获。将肠胃外给药和口服治疗视为一个整体，88例患者中共有54例实现了完全治愈。28例患者病情得到改善，由于仅在月经前出现少量痤疮丘疹，因此不再需要进一步治疗。实际上，6例患者也有改善，但在治疗中断后痤疮复发，因此必须进行维持治疗。将治疗方式分为肠胃外给药组和口服治疗组后，结果明显表明肠胃外给药治疗效果更好。肠胃外给药治疗效果比口服给药高出50%。我认为对任何形式的痤疮开始治疗时先进行一个疗程的注射是合适的，并根据观察到的效果转为口服治疗。无论如何，肠胃外给药和口服治疗的剂量都必须进行个体化调整。（图表：见正文）
