Martin S, Pitcher D, Tschen J, Wolf J E
J Am Acad Dermatol. 1980 Feb;2(2):117-23. doi: 10.1016/s0190-9622(80)80389-6.
Angioendotheliomatosis is a rare disorder with both cutaneous and systemic clinical presentations. We agree that there is evidence in the existing medical literature for the separation of reactive and malignant (neoplastic) variants of angioendotheliomatosis. These variants share similar histologic and ultrastructural features but seem clinically distinct. The reactive variant has been associated (four of seven cases, including our patient) with existing or preexisting subacute bacterial endocarditis.
血管内皮瘤病是一种罕见的疾病，具有皮肤和全身临床表现。我们认同现有医学文献中有证据表明血管内皮瘤病存在反应性和恶性（肿瘤性）变体之分。这些变体具有相似的组织学和超微结构特征，但临床症状似乎有所不同。反应性变体（包括我们的患者在内，7例中有4例）与现有的或先前存在的亚急性细菌性心内膜炎有关。
