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Biological activities of non-protein chromophores of antitumor protein antibiotics: auromycin and neocarzinostatin.

作者信息

Suzuki H, Miura K, Kumada Y, Takeuchi T, Tanaka N

出版信息

Biochem Biophys Res Commun. 1980 May 14;94(1):255-61. doi: 10.1016/s0006-291x(80)80214-2.

DOI:10.1016/s0006-291x(80)80214-2
PMID:6446307
Abstract
摘要

相似文献

1
Biological activities of non-protein chromophores of antitumor protein antibiotics: auromycin and neocarzinostatin.抗肿瘤蛋白抗生素的非蛋白质发色团的生物活性:金霉素和新制癌菌素。
Biochem Biophys Res Commun. 1980 May 14;94(1):255-61. doi: 10.1016/s0006-291x(80)80214-2.
2
Tumor-associated ganglio-N-triosylceramide. Target for antibody-dependent, avidin-mediated drug killing of tumor cells.肿瘤相关神经节-N-三糖神经酰胺。抗体依赖性、抗生物素蛋白介导的肿瘤细胞药物杀伤的靶点。
J Biol Chem. 1980 Nov 10;255(21):10509-16.
3
DNA damage in neocarzinostatin-, macromomycin-, and bleomycin-treated SV40 virions.
Mol Pharmacol. 1980 May;17(3):388-94.
4
Effect of nonprotein chromophore removal on neocarzinostatin action.去除非蛋白质发色团对新制癌菌素作用的影响。
Biochemistry. 1980 Apr 29;19(9):1767-73. doi: 10.1021/bi00550a007.
5
Urea treatment and pronase digestion of antitumor protein antibiotics, auromomycin and neocarzinostatin.
J Antibiot (Tokyo). 1980 Dec;33(12):1545-50. doi: 10.7164/antibiotics.33.1545.
6
Effects of an antitumor agent, ascofuranone, on the macromolecular syntheses of intact cells.抗肿瘤药物灰树花呋喃酮对完整细胞大分子合成的影响。
J Antibiot (Tokyo). 1983 Jul;36(7):892-9. doi: 10.7164/antibiotics.36.892.
7
Measurement of bleomycin, neocarzinostatin, and auromomycin cleavage of cell-free and intracellular simian virus 40 DNA and chromatin.博来霉素、新制癌菌素和金霉素对无细胞及细胞内猿猴病毒40 DNA和染色质切割作用的测定。
Mol Pharmacol. 1986 Oct;30(4):358-63.
8
NEOCARZINOSTATIN, AN ANTITUMOR ANTIBIOTIC OF HIGH MOLECULAR WEIGHT. ISOLATION, PHYSIOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES.新制癌菌素,一种高分子量抗肿瘤抗生素。分离、理化性质及生物活性
J Antibiot (Tokyo). 1965 Mar;18:68-76.
9
Biological activities and physicochemical properties of pre-neocarzinostatin and UV-irradiated neocarzinostatin.前新制癌菌素和紫外线照射新制癌菌素的生物活性及理化性质。
J Antibiot (Tokyo). 1980 Jan;33(1):110-3. doi: 10.7164/antibiotics.33.110.
10
Biological activity of the antitumor protein neocarzinostatin coupled to a monoclonal antibody by N-succinimidyl 3-(2-pyridyldithio)-propionate.
Biochem Biophys Res Commun. 1981 Jul 30;101(2):599-606. doi: 10.1016/0006-291x(81)91301-2.

引用本文的文献

1
Strategies and Approaches for Discovery of Small Molecule Disruptors of Biofilm Physiology.生物膜生理学小分子破坏剂的发现策略与方法。
Molecules. 2021 Jul 29;26(15):4582. doi: 10.3390/molecules26154582.
2
DNA breakage activity of the methanol extract of auromomycin.金霉素甲醇提取物的DNA断裂活性。
Cancer Chemother Pharmacol. 1981;7(1):41-50. doi: 10.1007/BF00258212.
3
Activation of neocarzinostatin chromophore and formation of nascent DNA damage do not require molecular oxygen.新制癌菌素生色团的激活和新生DNA损伤的形成不需要分子氧。
Nucleic Acids Res. 1985 Mar 11;13(5):1637-48. doi: 10.1093/nar/13.5.1637.
4
A tentative model of the intercalative binding of the neocarzinostatin chromophore to double-stranded tetranucleotides.新制癌菌素发色团与双链四核苷酸嵌入结合的初步模型。
Nucleic Acids Res. 1987 Mar 11;15(5):2175-89. doi: 10.1093/nar/15.5.2175.
5
Crystal structure analysis of auromomycin apoprotein (macromomycin) shows importance of protein side chains to chromophore binding selectivity.金霉素脱辅基蛋白(大分子霉素)的晶体结构分析表明蛋白质侧链对发色团结合选择性的重要性。
Proc Natl Acad Sci U S A. 1989 Sep;86(17):6587-91. doi: 10.1073/pnas.86.17.6587.
6
Kinetic analysis of the in vitro cell-killing action of neocarzinostatin.
Cancer Chemother Pharmacol. 1989;23(5):279-82. doi: 10.1007/BF00292404.