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Biological activity of the antitumor protein neocarzinostatin coupled to a monoclonal antibody by N-succinimidyl 3-(2-pyridyldithio)-propionate.

作者信息

Jung G, Köhnlein W, Lüders G

出版信息

Biochem Biophys Res Commun. 1981 Jul 30;101(2):599-606. doi: 10.1016/0006-291x(81)91301-2.

DOI:10.1016/0006-291x(81)91301-2
PMID:6458289
Abstract
摘要

相似文献

1
Biological activity of the antitumor protein neocarzinostatin coupled to a monoclonal antibody by N-succinimidyl 3-(2-pyridyldithio)-propionate.
Biochem Biophys Res Commun. 1981 Jul 30;101(2):599-606. doi: 10.1016/0006-291x(81)91301-2.
2
Immune suppression of anti-DNA antibody production using anti-idiotypic antibody-neocarzinostatin conjugates.使用抗独特型抗体-新制癌菌素缀合物对抗DNA抗体产生进行免疫抑制。
Methods Enzymol. 1989;178:422-32. doi: 10.1016/0076-6879(89)78031-9.
3
Inhibition of SV40 DNA synthesis by camptothecin and neocarzinostatin.
Mol Pharmacol. 1978 Nov;14(6):1156-66.
4
Mechanism of DNA degradation induced by neocarzinostatin in Bacillus subtilis.新制癌菌素诱导枯草芽孢杆菌中DNA降解的机制。
J Antibiot (Tokyo). 1975 Mar;28(3):229-36. doi: 10.7164/antibiotics.28.229.
5
DNA damage in neocarzinostatin-, macromomycin-, and bleomycin-treated SV40 virions.
Mol Pharmacol. 1980 May;17(3):388-94.
6
Biological activities of non-protein chromophores of antitumor protein antibiotics: auromycin and neocarzinostatin.抗肿瘤蛋白抗生素的非蛋白质发色团的生物活性：金霉素和新制癌菌素。
Biochem Biophys Res Commun. 1980 May 14;94(1):255-61. doi: 10.1016/s0006-291x(80)80214-2.
7
The generalization of pre-neocarzinostatin and antagonism of neocarzinostatin-induced DNA scission in vitro.
Biochim Biophys Acta. 1980 Jun 27;608(1):147-53. doi: 10.1016/0005-2787(80)90142-2.
8
A model for the activation and inactivation of neocarzinostatin, an antitumor protein.一种抗肿瘤蛋白新制癌菌素的激活和失活模型。
Biochim Biophys Acta. 1980 Jun 27;608(1):138-46. doi: 10.1016/0005-2787(80)90141-0.
9
Nucleotide specificity in DNA scission by neocarzinostatin.新制癌菌素切割DNA时的核苷酸特异性
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3603-7. doi: 10.1073/pnas.75.8.3603.
10
Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin.抗肿瘤蛋白新制癌菌素在体外对DNA链断裂的表征
Biochemistry. 1977 Feb 8;16(3):486-93. doi: 10.1021/bi00622a023.

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Gene transfer into hepatoma cell lines via the serpin enzyme complex receptor.通过丝氨酸蛋白酶抑制剂酶复合物受体将基因导入肝癌细胞系。
Am J Physiol. 1997 Aug;273(2 Pt 1):G545-52. doi: 10.1152/ajpgi.1997.273.2.G545.
2
Effects of neocarzinostatin-chimeric Fab conjugates on the growth of human pancreatic carcinoma xenografts.新制癌菌素-嵌合Fab缀合物对人胰腺癌异种移植瘤生长的影响。
Br J Cancer. 1996 May;73(10):1178-82. doi: 10.1038/bjc.1996.227.
3
Follow-up study of patients treated with monoclonal antibody-drug conjugate: report of 77 cases with colorectal cancer.
单克隆抗体-药物偶联物治疗患者的随访研究：77例结直肠癌病例报告
Jpn J Cancer Res. 1993 Sep;84(9):976-81. doi: 10.1111/j.1349-7006.1993.tb00188.x.
4
Production, binding and cytotoxicity of human/mouse chimeric monoclonal antibody-neocarzinostatin conjugate.人/鼠嵌合单克隆抗体-新制癌菌素缀合物的制备、结合及细胞毒性
Jpn J Cancer Res. 1993 Nov;84(11):1190-4. doi: 10.1111/j.1349-7006.1993.tb02820.x.
5
Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.利用修饰的表面活性物质相关蛋白B将DNA递送至培养的气道细胞。
Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2547-51. doi: 10.1073/pnas.91.7.2547.
6
Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor.通过靶向聚合免疫球蛋白受体将基因转移到动物气道上皮中。
J Clin Invest. 1995 Feb;95(2):493-502. doi: 10.1172/JCI117690.
7
Selective elimination of anti-DNA antibody-producing cells by antiidiotypic antibody conjugated with neocarzinostatin.通过与新制癌菌素偶联的抗独特型抗体选择性清除产生抗DNA抗体的细胞。
J Clin Invest. 1986 Apr;77(4):1382-6. doi: 10.1172/JCI112444.
8
Selective toxicity of neocarzinostatin-monoclonal antibody conjugates to the antigen-bearing human melanoma cell line in vitro.新制癌菌素-单克隆抗体缀合物对体外携带抗原的人黑色素瘤细胞系的选择性毒性。
Cancer Immunol Immunother. 1985;20(1):85-90. doi: 10.1007/BF00199779.
9
Therapeutic treatment of New Zealand mouse disease by a limited number of anti-idiotypic antibodies conjugated with neocarzinostatin.用有限数量的与新制癌菌素偶联的抗独特型抗体对新西兰小鼠疾病进行治疗性处理。
J Clin Invest. 1990 Sep;86(3):769-76. doi: 10.1172/JCI114773.
10
Specific cytotoxic effect of neocarzinostatin conjugated to monoclonal antibody A7 on human pancreatic carcinoma.
Gastroenterol Jpn. 1990 Apr;25(2):244-8. doi: 10.1007/BF02776823.