Bruguerolle B, Jadot G, Valli M, Bouyard P
C R Seances Soc Biol Fil. 1980;173(6):1095-8.
Statistical study of Cimetidine effects on estrous cycle of the rat have been performed, by daily vaginal smears, for twenty one days with doses nearly similar to those used in human therapy. Our data showed that Cimetidine did not significantly modify the evolution of estrous cycles.
通过每日阴道涂片,以接近人类治疗中使用的剂量,对西咪替丁对大鼠发情周期的影响进行了为期21天的统计研究。我们的数据表明,西咪替丁并未显著改变发情周期的变化。