Richter G
Contact Dermatitis. 1980 Apr;6(3):183-6. doi: 10.1111/j.1600-0536.1980.tb05595.x.
Observations on nine patients with occupational dermatitis from methylisothiocyanate (MITC) lead to the following conclusions: 1. MITC causes primarily a toxic dermatitis, but as a strong sensitizer it induces sensitization as well. 2. Cross reactions between MITC and benzylisothiocyanate, the active agent of Sulbentin antimycotics, were not seen. 3. In patient a MITC acid burn on one foot and leg caused systemic poisoning from absorption with reversible damage to the liver parenchyma.
对9例因异硫氰酸甲酯(MITC)导致职业性皮炎的患者的观察得出以下结论:1. MITC主要引起中毒性皮炎,但作为一种强致敏剂,它也会引发致敏反应。2. 未观察到MITC与舒布硫因抗真菌药的活性剂苄基异硫氰酸酯之间的交叉反应。3. 患者a的一只脚和腿部被MITC酸灼伤,因吸收导致全身中毒,肝实质出现可逆性损伤。