Marks J M
Drugs. 1980 Jun;19(6):429-36. doi: 10.2165/00003495-198019060-00003.
Psoriasis varies so much in severity and clinical pattern that there is no 'best' treatment. Topical treatment with dithranol, tar or wisely used corticosteroids is preferable to systemic treatment, except in severe forms of psoriasis where systemic corticosteroids or antimitotic drugs, especially methotrexate, may be necessary. Photochemotherapy with PUVA has come to stay and can certainly be used as first-line treatment in those with extensive plaque psoriasis who are over 60 years of age. Its role in treating younger patients is still being asssssed, particularly with regard to possible long term side effects, but it is likely that eventually its use will be extended.
银屑病在严重程度和临床症状方面差异极大，以至于不存在“最佳”治疗方法。除了在严重型银屑病中可能需要使用全身性皮质类固醇或抗有丝分裂药物（尤其是甲氨蝶呤）外，外用蒽林、焦油或合理使用的皮质类固醇比全身治疗更可取。补骨脂素加长波紫外线光化学疗法（PUVA）已被广泛应用，对于60岁以上患有广泛斑块状银屑病的患者，它无疑可作为一线治疗方法。其在治疗年轻患者中的作用仍在评估中，特别是考虑到可能的长期副作用，但最终其应用可能会扩大。
