噬菌体λ中Chi刺激重组的方向性和非互惠性
Directionality and nonreciprocality of Chi-stimulated recombination in phage lambda.
作者信息
Stahl F W, Stahl M M, Malone R E, Crasemann J M
出版信息
Genetics. 1980 Feb;94(2):235-48. doi: 10.1093/genetics/94.2.235.
Abstract
Chi's are genetic elements that stimulate generalized recombination in their locale in phage lambda. All Chi's wherever located on lambda's chromosome, act asymmetrically in crosses blocked in DNA replication: (1) They stimulate exchange primarily to their left on the conventional lambda map, and (2) the stimulated exchange is frequently nonreciprocal, the recombinant carrying the Chi element being produced less often than the complementary product.
摘要
χ序列是能在λ噬菌体的局部区域刺激广泛重组的遗传元件。无论位于λ噬菌体染色体的何处，所有χ序列在DNA复制受阻的杂交中都表现出不对称性：（1）在传统的λ噬菌体图谱上，它们主要刺激其左侧的交换；（2）受刺激的交换通常是非相互的，携带χ序列的重组体产生的频率低于互补产物。
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