Samorukov A E
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(3):348-53.
In 55 patients with parkinsonism and 9 patients with Huntington's chorea the lipid spectrum of the serum and erythrocytes was examined by thin-layer chromatography on silica gel. Certain disturbances of the lipid metabolism were revealed both in the patients with parkinsonism and Huntington's chorea. The lipid spectra in patients with the tremulous and the rigid forms of parkinsonism were found to be different, and the depth of the lipid metabolism disturbances depended on the severity of the clinical manifestations. The disturbances of the lipid metabolism in erythrocytes may point to a generalized character of the defect. Participation of biogenic amines in the lipid metabolism pathology in patients with involvement of the paleostriatum system is suggested.
对55例帕金森病患者和9例亨廷顿舞蹈症患者，采用硅胶薄层层析法检测血清和红细胞的脂质谱。帕金森病患者和亨廷顿舞蹈症患者均出现了某些脂质代谢紊乱。发现震颤型和僵直型帕金森病患者的脂质谱不同，脂质代谢紊乱的程度取决于临床表现的严重程度。红细胞脂质代谢紊乱可能表明缺陷具有全身性。提示生物胺参与了旧纹状体系统受累患者的脂质代谢病理过程。
