Schröder R, Holmin T
Helv Chir Acta. 1980 Feb;46(5-6):799-801.
17 patients with primary carcinoma of the gallbladder were studied. In 7 cases a palliative operation for biliary or gastrointestinal obstruction was performed, in 6 patients a biopsy only. None of the 4 patients undergoing a more "radical" procedure survived 2 years. The main symptoms were pain, jaundice and weight loss. Other manifestations were acute cholecystitis and pyloric obstruction. A correct preoperative diagnosis was established only in 3 cases. Most of the small tumors are discovered by the surgeon who performs a cholecystectomy for stones. Simple cholecystectomy, however, is a palliative procedure in most cases with carcinoma involving all layers of the wall.
对17例原发性胆囊癌患者进行了研究。7例因胆道或胃肠道梗阻行姑息性手术,6例仅做了活检。接受更“根治性”手术的4例患者中无一例存活2年。主要症状为疼痛、黄疸和体重减轻。其他表现为急性胆囊炎和幽门梗阻。仅3例术前诊断正确。大多数小肿瘤是由因结石而行胆囊切除术的外科医生发现的。然而,在大多数癌累及胆囊壁全层的病例中,单纯胆囊切除术是一种姑息性手术。