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[德意志民主共和国的威尔逊氏病。III. 诊断与治疗]

[Wilson's disease in the German Democratic Republic. III. Diagnosis and therapy].

作者信息

Lössner J, Storch W, Bachmann H, Biesold D, Kühn H J

出版信息

Z Gesamte Inn Med. 1980 Feb 15;35(4):161-6.

PMID:6447415
Abstract

Taking into consideration the manifold symptomatology of Wilson's disease on the one hand and the necessity of an early--possibly already at the asymptomatic stage before the 6th year of life--diagnostic ascertainment on the other hand, the diagnostic approach performed in the GDR is described. Furthermore, the directives of treatment and the successes of treatment are discussed as well as the various side-effects of the D-penicillamine therapy described, in which case the severe nephrotic syndromes are particularly considered.

摘要

一方面考虑到威尔逊氏病的多种症状,另一方面考虑到早期诊断的必要性——可能在6岁之前的无症状阶段就进行诊断——本文描述了民主德国所采用的诊断方法。此外,还讨论了治疗指南和治疗效果,以及所描述的D-青霉胺疗法的各种副作用,其中特别考虑了严重的肾病综合征。

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