Endre L, Osváth P, Péter F
Allerg Immunol (Leipz). 1980;26(1):15-20.
Milk- and egg-specific serum IgE levels of 62 respiratoric and/or skin allergic children have been measured. 8 (14,5%) from clinically milk- and 3 (13,6%) of 22 egg-allergic children had abnormally high specific IgE globulin levels. The positive results were measured mostly in boys (10 boys from 11 positive patients). 4 children (28,5%) from 14 patients with allergic diseases having low IgA levels had abnormally high specific IgE concentrations. Authors suppose that the low positivity rate is caused--besides others--by the examined antigen's heterogeneity. The RAST with complex antigens is useful to diagnose only the extreme cases. Our data show the necessity of using purified antigens, to make this method more specific.
已对62名患有呼吸道和/或皮肤过敏的儿童进行了牛奶和鸡蛋特异性血清IgE水平检测。在临床诊断为牛奶过敏的儿童中，有8名（14.5%），在22名鸡蛋过敏儿童中有3名（13.6%）的特异性IgE球蛋白水平异常升高。阳性结果大多出现在男孩中（11名阳性患者中有10名男孩）。14名IgA水平较低的过敏性疾病患儿中有4名（28.5%）特异性IgE浓度异常升高。作者认为，除其他因素外，检测抗原的异质性导致了阳性率较低。使用复合抗原的放射变应原吸附试验仅对极端病例的诊断有用。我们的数据表明，有必要使用纯化抗原，以使该方法更具特异性。
