Harihara S, Monna T, Yamamoto S
Gastroenterol Jpn. 1980;15(4):380-4.
This study was conducted on 139 patients with liver cirrhosis with diffuse formation of the nodules on the liver surface demonstrated by peritoneoscopic examination. In all of these patients, the diagnosis had been established more than 5 years ago, and the cumulative survival rates were calculated by the life table method. The relationship between the survival rate and macroscopic findings on the surface of the liver was studied and the following conclusions were drawn. 1) The 5 and 10 year survival rates in patients with cirrhosis with swelling of the right lobe were as high as 71.2 and 53.4% respectively and were significantly higher than the corresponding figures of 30.0 and 12.7% in patients with cirrhosis with right lobe atrophy (pless than0.001). 2) The 5 year survival rate in patients with cirrhosis of the small nodular type with a predominance of nodules with diameters less than 3mm was a high as 70.6%. This was significantly higher than that in patients with cirrhosis of the medium and large nodular type with nodules measuring more than 3mm in diameter where the 5 year survival rate was 36.0% (pless than0.001). 3) The 5 year survival rate in patients with cirrhosis of the narrow stromal type was as high as 61.4%, being significantly higher than that in patients with cirrhosis of the broad and mixed stromal type where the 5 year survival rate was 43.2% (pless than0.05). The observation of the surface pattern of the liver by peritoneoscopy appears to be of great predictive value for the prognosis of liver cirrhosis.
本研究对139例经腹腔镜检查证实肝脏表面有弥漫性结节形成的肝硬化患者进行。所有这些患者的诊断均已确立5年以上，采用寿命表法计算累积生存率。研究了生存率与肝脏表面宏观表现之间的关系，并得出以下结论。1）右叶肿大的肝硬化患者的5年和10年生存率分别高达71.2%和53.4%，显著高于右叶萎缩的肝硬化患者相应的30.0%和12.7%（P<0.001）。2）以直径小于3mm的结节为主的小结节型肝硬化患者的5年生存率高达70.6%。这显著高于直径大于3mm的中、大结节型肝硬化患者，后者的5年生存率为36.0%（P<0.001）。3）窄间质型肝硬化患者的5年生存率高达61.4%，显著高于宽间质型和混合型肝硬化患者，后者的5年生存率为43.2%（P<0.05）。通过腹腔镜检查观察肝脏表面形态似乎对肝硬化的预后具有很大的预测价值。
