Durand G, Dumont J P, Appel M, Durand D, Davy J, Féger J, Agneray J
Horm Metab Res. 1980;12(6):247-51. doi: 10.1055/s-2007-996259.
The possible correlation between sialic acid content of hepatocyte plasma membranes, and their binding capacity was investigated. For that purpose, [3H] asialotransferrin binding was tested with hepatocytes from both normal and streptozotocin treated rats. The observed decrease in binding capacity was parallel to a decrease in the sialic acid content Insulin therapy restored simultaneously normal blood glucose level, hepatic membrane sialic acid content and binding capacity.
研究了肝细胞质膜唾液酸含量与其结合能力之间的可能相关性。为此，用正常大鼠和链脲佐菌素处理的大鼠的肝细胞检测了[3H]去唾液酸转铁蛋白结合情况。观察到的结合能力下降与唾液酸含量的下降平行。胰岛素治疗同时恢复了正常血糖水平、肝细胞膜唾液酸含量和结合能力。
