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[类风湿关节炎中的抑制细胞活性]

[The suppressor cell activity in rheumatoid arthritis].

作者信息

Vogelsang H, Hein G, Jäger L

出版信息

Z Rheumatol. 1980 May-Jun;39(5-6):141-4.

PMID:6447962
Abstract

The rate of 3H-thymidine incorporation into peripheral blood lymphocytes was determined immediately after the addition of 1 microgram of Con A and after 24 h of preincubation period the stimulation in normal controls was 3 times higher than after the immediate addition of mitogen. In rheumatics the increase was 1,7-fold only. The results were interpreted as indicating a lack of suppressor cell activity in the patients with rheumatoid arthritis.

摘要

加入1微克刀豆球蛋白A后立即测定3H-胸腺嘧啶核苷掺入外周血淋巴细胞的速率,在预温育24小时后,正常对照组的刺激作用比立即加入促细胞分裂剂后高3倍。在风湿患者中,增加仅为1.7倍。结果被解释为表明类风湿性关节炎患者缺乏抑制细胞活性。

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