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[类风湿关节炎中短寿命抑制性淋巴细胞的活性]

[Activity of short-lived suppressor lymphocytes in rheumatoid arthritis].

作者信息

Vasil'eva E V, Nasonov E L, Mazneva L M, Saĭkovskiĭ R K, Sura V V

出版信息

Ter Arkh. 1985;57(7):98-102.

PMID:2931852
Abstract

Activity of short-lived suppressor lymphocytes was studied in 26 patients with rheumatoid arthritis. Of these, 14 patients had diverse systemic manifestations: rheumatoid nodules, polyneuropathy. Sjögren's syndrome, and Felty's syndrome. It was established that attenuation of the suppressor activity in rheumatoid arthritis is characteristic of patients with systemic manifestations, who show a high level of circulating immune complexes of rheumatoid factors. The most informative data were obtained as a result of the use of the suboptimal dose of Con A having suppressor activity.

摘要

对26例类风湿性关节炎患者的短寿命抑制淋巴细胞活性进行了研究。其中14例患者有多种全身表现:类风湿结节、多发性神经病、干燥综合征和费尔蒂综合征。已确定类风湿性关节炎患者抑制活性减弱是有全身表现患者的特征,这些患者类风湿因子的循环免疫复合物水平较高。使用具有抑制活性的次优剂量刀豆蛋白A可获得最有用的数据。

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