Goette D K, Odom R B
Cutis. 1980 Oct;26(4):406-9.
Widespread dermatitis developed in three women after use of vaginal preparations. Besides allergic contact dermatitis, these cases involved erythema multiforme and a photosensitive eruption. Antigen absorption into the general circulation through the vaginal wall, and its deposition at distant skin sites, appeared to account for the spread of the eruption. This type of eruption is akin to the systemic, eczematous, contact-type dermatitis mediated by a systemically given drug in a primarily cutaneously sensitized person.
三名女性在使用阴道制剂后出现了广泛的皮炎。除过敏性接触性皮炎外，这些病例还涉及多形红斑和光敏性皮疹。抗原通过阴道壁吸收进入全身循环，并沉积在远处的皮肤部位，这似乎是皮疹扩散的原因。这种类型的皮疹类似于在主要经皮肤致敏的个体中由全身给药的药物介导的全身性、湿疹性、接触型皮炎。
