Gaillard D, Birembaut P, Dupouy D, Arnaudies J, Adnet J J
C R Seances Soc Biol Fil. 1980;174(3):344-6.
The presence of cholinergic nerve fibers is studied in 30 suction rectal biopsy specimens from 5 days to 7 years old children. An increase in numbers and size of cholinergic fibers in the lamina propria and muscularis mucosae and absence of submucosa ganglion cells are related to 7 Hirschsprung's diseases. In the neonates acetylcholinesterase activity may not be strong enough to stain cholinergic fibers and makes the diagnosis more difficult.
对30例5天至7岁儿童的直肠吸引活检标本进行了胆碱能神经纤维的研究。固有层和黏膜肌层中胆碱能纤维数量和大小的增加以及黏膜下层神经节细胞的缺失与7例先天性巨结肠病有关。在新生儿中，乙酰胆碱酯酶活性可能不够强，无法使胆碱能纤维染色，从而使诊断更加困难。
