Rodier F, Gabarro-Arpa J, Ehrlich R, Reiss C
C R Seances Acad Sci D. 1980 Sep 15;291(2):199-202.
The DNA sequences of three bacteriophages are analysed in order to localise those parts coding for a protein. A weak stability on the DNA molecule allows us to characterize the beginning and the end of genes. A survey of the codons used shows that the cause for this weak stability is the systematic use of A-T bases in third position, which is made possible by the degeneracy of the genetic code.
为了定位编码蛋白质的部分,对三种噬菌体的DNA序列进行了分析。DNA分子上的弱稳定性使我们能够确定基因的起始和终止位置。对所使用密码子的研究表明,这种弱稳定性的原因是在密码子第三位系统地使用A-T碱基,这是由遗传密码的简并性所导致的。