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通过琼脂糖凝胶等电聚焦法测定的PGM1亚型

PGM1 subtypes determined by agarose gel isoelectrofocusing.

作者信息

Weidinger S, Schwarzfischer F

出版信息

Z Rechtsmed. 1980;84(3):221-4. doi: 10.1007/BF01866573.

Abstract

PGM1 subtypes were determined in red cell hemolysates by isoelectric focusing on agarose gel plates. By this modified procedure PGM1 subtypes may be readily classified. Nine of the 10 expected phenotypes were found in a sample of 470 unrelated individuals from Southern Germany. The frequencies for the four alleles were found to be: PGM1(1+) = 0.212, PGM1(1-) = 0.1224, PGM1(2+) = 0.2043, PGM1(2-) = 0.0521.

摘要

通过在琼脂糖凝胶板上进行等电聚焦,在红细胞溶血产物中确定PGM1亚型。通过这种改良方法,PGM1亚型可以很容易地分类。在来自德国南部的470名无亲缘关系个体的样本中,发现了10种预期表型中的9种。发现四个等位基因的频率分别为:PGM1(1+) = 0.212,PGM1(1-) = 0.1224,PGM1(2+) = 0.2043,PGM1(2-) = 0.0521。

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