Gannushkina I V, Zhirnova I G, Alieva L M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(9):1297-1301.
Results of examining the sera of 11 normal donors and 37 patients with various neutogenetic diseases using, the Coons indirect immunofluorescence technique are presented. The patients' immunoglobulins could be better fixed on nervous tissue components than those of the control donors. This seems likely to be due to both a rise in the content of serum immunoglobulins and accumulation of specific anticerebral antibodies in the patients' blood. It is suggested that in all cases of using indirect immunofluorescence the quantitative determination of immunoglobulins and serum titration should be carried out.
本文呈现了使用孔氏间接免疫荧光技术检测11名正常供血者和37名患有各种神经遗传性疾病患者血清的结果。与对照供血者相比，患者的免疫球蛋白能更好地固定在神经组织成分上。这似乎是由于患者血清中免疫球蛋白含量升高以及特异性抗脑抗体在血液中积累所致。建议在所有使用间接免疫荧光的情况下，都应进行免疫球蛋白的定量测定和血清滴定。
