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[关于抗体依赖性细胞毒性或ADCC现象的最新数据]

[Recent data on antibody-dependent cell cytotoxicity, or the ADCC phenomenon].

作者信息

Descamps B

出版信息

C R Seances Soc Biol Fil. 1980;174(4):741-9.

PMID:6449252
Abstract

A review of the recent literature on ADCC affords strong evidence that this cytotoxicity phenomenon, discovered fortuitously in 1965, can no longer be considered only a laboratory curiosity. It is, in fact, more than probable that ADCC is involved in most defense mechanisms of the individual from allograft immunity and antitumoral defense to the resistance of the host against most pathogens.

摘要

对近期有关抗体依赖的细胞介导的细胞毒性作用(ADCC)的文献综述提供了有力证据,表明这种于1965年偶然发现的细胞毒性现象,再也不能仅仅被视为一种实验室现象。事实上,ADCC很可能参与了个体的大多数防御机制,从同种异体移植免疫、抗肿瘤防御到宿主对大多数病原体的抵抗。

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