用于细胞介导免疫的毛细管白细胞黏附抑制试验：豚鼠短暂细菌感染的影响
Capillary tube leucocyte adherence inhibition assay for cell-mediated immunity: effects of transient bacterial infection in guinea-pigs.
作者信息
Ballard C M, Dickinson J P
出版信息
Clin Exp Immunol. 1980 May;40(2):383-7.
Adherence of guinea-pig leucocytes to glass, and changes of adherence caused by antigen challenge, were measured during a 3-month period in which an idiogenic, fortuitous bacterial infection passed though the main guinea-pig colony. Expected responses were found in SPF animals, and, at the beginning and end of this period, in stock animals and those immunized with Freund's complete adjuvant with or without added keyhole limpet haemocyanin. During active infection, all non-SPF animals showed enhanced adherence changes whilst SPF animals continued to give expected responses. The implications for use of leucocyte adherence inhibition tests with human subjects are discussed.
在为期3个月的时间里，测量了豚鼠白细胞对玻璃的黏附性以及抗原激发引起的黏附性变化。在此期间，豚鼠主要群体中发生了一次偶发性的细菌感染。在无特定病原体（SPF）动物中发现了预期的反应，并且在这段时间开始和结束时，在普通饲养动物以及用弗氏完全佐剂免疫（添加或未添加钥孔戚血蓝蛋白）的动物中也发现了预期反应。在感染活跃期，所有非SPF动物的黏附性变化增强，而SPF动物继续给出预期反应。本文讨论了白细胞黏附抑制试验在人类受试者中的应用意义。
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