Mang W L, Hammer C, Gruber F
Laryngol Rhinol Otol (Stuttg). 1980 Apr;59(4):227-31.
New insights into the cellular control mechanisms of immune reactivity may become important to physicians who manage patients with cancer. In 29 patients with tonsillar carcinoma, not only humoral, but also cellular mechanisms with major emphasis on regulator cells, i.e. suppressor cells, have been investigated. It seems from these cells, as if an unspecific suppressive activity measured in these patients could give a better opportunity to trace the immunological immune reaction against this tumor and give thus a chance for "specific immunotherapeutic regimens" which should on the one hand stress the activation of the host's tumor cytotoxicity and on the other hand eliminate the function of suppressor cells.
对免疫反应细胞控制机制的新见解可能对治疗癌症患者的医生很重要。在29例扁桃体癌患者中，不仅研究了体液机制，还重点研究了以调节细胞即抑制细胞为主的细胞机制。从这些细胞来看，似乎在这些患者中测得的非特异性抑制活性可能为追踪针对这种肿瘤的免疫反应提供更好的机会，从而为“特异性免疫治疗方案”提供机会，该方案一方面应强调激活宿主的肿瘤细胞毒性，另一方面消除抑制细胞的功能。
