Johansen J P, Fossgreen J, Hansen H H
Acta Orthop Scand. 1980 Aug;51(4):617-20. doi: 10.3109/17453678008990851.
99m technetium methylene diphosphate was used for whole body scanning and linear multiplane tomoscanning in 10 patients with typical clinical symptoms of prolapsed disc, in order to investigate whether there would be an increased focal accumulation corresponding to the bone structures adjacent to the affected disc. The diagnosis of a prolapsed disc was confined by amipaque myelography, carried out in 9 patients, and finally verified at operation. In none of the 10 cases could accumulation of radioactivity in the bony structures of the affected lumar segment be demonstrated. Consequently this method has not been adopted for the diagnosis of prolapsed lumbar discs. However it was demonstrated that 99m technetium methylene diphosphate scintillography is useful in the differential diagnosis of anchylosing spondylitis and discitis.
对10例有典型椎间盘突出临床症状的患者，使用99m锝亚甲基二膦酸盐进行全身扫描和线性多平面断层扫描，以研究在受影响椎间盘相邻的骨骼结构处是否会有局灶性放射性聚集增加。9例患者进行了阿米培克脊髓造影以明确椎间盘突出的诊断，最终在手术中得到证实。10例患者中，均未发现受影响腰椎节段的骨骼结构有放射性聚集。因此，该方法未被用于诊断腰椎间盘突出。然而，已证明99m锝亚甲基二膦酸盐闪烁扫描在强直性脊柱炎和椎间盘炎的鉴别诊断中是有用的。
