Schäffner H
Allerg Immunol (Leipz). 1980;26(2):95-110.
With respect to our present knowledge about the functions of macrophages in relation to the immune responses the most important functions include elimination and processing of the antigen; antigen presentation and induction of immune response; immune regulation by several inhibitory and activating factors; binding of T cell products, which regulate B cell functions (helper and suppressor factors); helper cell induction; cytotoxicity, bactericide and tumoricide activities after stimulation by T cells. In the present time most research activities are directed to the interactions of T cells and macrophages. These interactions depend mainly from genetically determined structures of the cell membranes (Ia antigens).
就我们目前对巨噬细胞在免疫反应中功能的了解而言，最重要的功能包括抗原的清除和加工；抗原呈递及免疫反应的诱导；通过多种抑制和激活因子进行免疫调节；结合调节B细胞功能的T细胞产物（辅助因子和抑制因子）；辅助细胞诱导；在T细胞刺激后产生细胞毒性、杀菌和杀肿瘤活性。目前，大多数研究活动都集中在T细胞与巨噬细胞的相互作用上。这些相互作用主要取决于细胞膜的遗传决定结构（Ia抗原）。
