Vincent J P, Vignon J, Kartalovski B, Lazdunski M
Eur J Pharmacol. 1980 Nov 7;68(1):73-7. doi: 10.1016/0014-2999(80)90064-3.
[3H]Phencyclidine has a tendency to adsorb to filters used in binding experiments. The spinal binding techniques that should be used to overcome this difficulty are described. The affinity of [3H]phencyclidine for its brain receptor was 4 times higher in a medium containing 5 mM salt than in a medium containing 50 mM salt.