Vincent J P, Vignon J, Kartalovski B, Lazdunski M
Eur J Pharmacol. 1980 Nov 7;68(1):79-82. doi: 10.1016/0014-2999(80)90065-5.
Phencyclidine and its derivatives bind specifically and reversibly to rat brain and peripheral organs. Binding characteristics are different in brain, lung, kidney, heart and liver. Affinities of phencyclidines for the brain receptor but not those for peripheral organs are correlated with the pharmacological activities of phencyclidines as measured in the rotarod test.
苯环利定及其衍生物能特异性且可逆地与大鼠脑及外周器官结合。在脑、肺、肾、心和肝中的结合特性有所不同。苯环利定对脑受体的亲和力，而非对外周器官的亲和力，与在转棒试验中所测定的苯环利定的药理活性相关。
