Stachura J, Tarnawski A, Bogdal J, Krause W, Ivey K
Gastroenterology. 1981 Mar;80(3):474-81.
We studied the effects of glucagon (2 mg intravenously) on the histochemical localization and staining intensity of 10 enzymes in human gastric mucosa. Glucagon caused a significant increase in the histochemical activity of glucose-6-phosphate dehydrogenase in the undifferentiated neck cells and mucous cells of the foveolae and of ATPase activity in and around the mucosal capillary walls. Glucagon also stimulated mucus secretion from the surface epithelial cells. These changes were observed 15 and 30 min after glucagon in the oxyntic, but no pyloric mucosa. they indicate that glucagon, in addition to its effect on parietal cells, also affects other structures in human gastric mucosa.
我们研究了胰高血糖素（静脉注射2毫克）对人胃黏膜中10种酶的组织化学定位和染色强度的影响。胰高血糖素使胃小凹未分化颈部细胞和黏液细胞中葡萄糖-6-磷酸脱氢酶的组织化学活性显著增加，并使黏膜毛细血管壁及其周围的ATP酶活性显著增加。胰高血糖素还刺激表面上皮细胞分泌黏液。在胃底黏膜注射胰高血糖素15分钟和30分钟后观察到了这些变化，但在幽门黏膜中未观察到。这表明胰高血糖素除了对壁细胞有作用外，还会影响人胃黏膜中的其他结构。
