Treves S, Fogle R, Lang P
Am J Cardiol. 1980 Dec 18;46(7):1247-55. doi: 10.1016/0002-9149(80)90295-7.
Cardiac nuclear imaging (radionuclide angiography, electrocardiographic gated ventriculography and myocardial scintigraphy) provides structural and functional information simultaneously. This method extracts accurate quantitation of cardiovascular hemodynamics and unique information regarding myocardial perfusion. It is a reliable and relatively simple and atraumatic technique because the only discomfort to the patient is a simple intravenous injection. These studies are carried out rapidly in out- or inpatients. Radionuclide angiography is ideal also to assess the effect of exercise, oxygen or drugs on cardiac function. The radiation exposure associated with current nuclear imaging is within the range of common radiographic procedures and many times lower than that of cardiac catheterization. The use of newer radionuclides such as iridium-191m with a physical half-life of 4.96 seconds will result in a dramatic decrease in the radiation exposure to patients undergoing radionuclide angiography. Also, newer and smaller computerized gamma cameras will provide studies of improved spatial resolution and accuracy. The future of pediatric applications of cardiac nuclear imaging is bright.
心脏核成像(放射性核素血管造影、心电图门控心室造影和心肌闪烁显像)可同时提供结构和功能信息。该方法能准确量化心血管血流动力学,并提供有关心肌灌注的独特信息。它是一种可靠且相对简单、无创的技术,因为患者唯一的不适只是一次简单的静脉注射。这些检查在门诊或住院患者中都能快速完成。放射性核素血管造影对于评估运动、吸氧或药物对心脏功能的影响也很理想。当前核成像相关的辐射暴露在普通放射检查的范围内,且比心脏导管检查低很多倍。使用物理半衰期为4.96秒的新型放射性核素如铱-191m,将显著降低接受放射性核素血管造影患者的辐射暴露。此外,更新型、更小的计算机化伽马相机将提供空间分辨率和准确性更高的检查。心脏核成像在儿科应用的前景广阔。