Marotte J H, Frottier J, Lord G, Blanchard J P, Guillamon J L, Goutard L, Servant J
Rev Chir Orthop Reparatrice Appar Mot. 1980 Oct;66(7):409-16.
The authors have studied the rate of infection after 14000 orthopaedic interventions performed in the same hospital during the period between 1971 and 1978. 1020 of these were performed in a vertical air flow enclosure with a clearance of air at a rate of 425 times per hour. The others were performed in the conventional operating theatre with an air clearance of 22 times per hour. The density of particles was found to be 50 to 100 times lower at the level of the incision in cases operated on under vertical flow. Depsite this, the rate of infection was 0.7p. 100 in the conventional theatre and 1.4p. 100 in the vertical flow theatre. However, if the study was limited to hip prostheses (1382 cases), the rate of infection was about the same: 2,9p. 100 in conventional theatres and 3,2p. 100 in vertical flow enclosures. It is concluded that the role of a vertical air flow enclosure in decreasing the rate of post-operative infection in doubtful. The authors recall the effects of previous operations on liability to infection and consider that the use of cement may increase the incidence of infection. They advocate the use of cementless, self-locking total prostheses.
作者研究了1971年至1978年期间在同一家医院进行的14000例骨科手术后的感染率。其中1020例手术是在垂直气流隔离室内进行的，空气交换率为每小时425次。其余手术则在传统手术室进行，空气交换率为每小时22次。发现在垂直气流下进行手术的病例中，切口处的颗粒密度要低50至100倍。尽管如此，传统手术室的感染率为0.7%，垂直气流手术室的感染率为1.4%。然而，如果研究仅限于髋关节置换术（1382例），感染率大致相同：传统手术室为2.9%，垂直气流隔离室为3.2%。得出的结论是，垂直气流隔离室在降低术后感染率方面的作用值得怀疑。作者回顾了先前手术对感染易感性的影响，并认为使用骨水泥可能会增加感染发生率。他们提倡使用无骨水泥、自锁式全假体。
