肥大细胞稳定剂化合物FPL 55618可减轻慢性低氧大鼠的右心室肥厚和肺肥大细胞增生。
Mast cell stabilizing compound FPL 55618 reduces right ventricular hypertrophy and lung mast cell hyperplasia in chronically hypoxic rats.
作者信息
Kay J M, Suyama K L, Keane P M
出版信息
Experientia. 1981 Jan 15;37(1):75-6. doi: 10.1007/BF01965579.
PMID:6451449
Abstract
Rats treated with chronic hypobaric hypoxia (21 days, 380 Torr) and mast cell stabilizing compound FPL 55618 had significantly less right ventricular hypertrophy and lung mast cell hyperplasia than rats subjected to chronic hypoxia alone. Right ventricular blood pressure was not reduced.
摘要
接受慢性低压缺氧（21天，380托）和肥大细胞稳定剂化合物FPL 55618治疗的大鼠，与仅接受慢性缺氧的大鼠相比，右心室肥大和肺肥大细胞增生明显减少。右心室血压未降低。
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