原噬菌体Mu诱导对相邻宿主基因表达的影响。
Effects of prophage Mu induction on expression of adjacent host genes.
作者信息
Dubow M S, Bukhari A I
出版信息
Mol Biol Rep. 1980 Dec 31;6(4):229-34. doi: 10.1007/BF00777530.
PMID:6451799
Abstract
The extent of induction and approximate amount of DNA replication of a Mu prophage carrying a gene for ampicillin resistance can be monitored by assaying the level of beta-lactamase. The expression of the lacZ gene adjacent to either end of an induced Mu prophage remains virtually unaffected, until late in the Mu lytic cycle, while Mu DNA is replicating and transposing.
摘要
携带氨苄青霉素抗性基因的 Mu 原噬菌体的诱导程度和 DNA 复制的大致量可通过检测β-内酰胺酶的水平来监测。在 Mu 溶菌周期后期，当 Mu DNA 正在复制和转座时，诱导的 Mu 原噬菌体两端相邻的 lacZ 基因的表达几乎不受影响。
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