炎症性肠病和脾功能减退患者的免疫功能受损：对静脉注射φX174的反应。
Impaired immunity in patients with inflammatory bowel disease and hyposplenism: the response to intravenous phi X174.
作者信息
Ryan F P, Jones J V, Wright J K, Holdsworth C D
出版信息
Gut. 1981 Mar;22(3):187-9. doi: 10.1136/gut.22.3.187.
Abstract
Eight patients with inflammatory bowel disease were tested for their ability to mount a serological response to the intravenous particulate antigen phi X174. Seven patients had extensive ulcerative colitis and one patient extensive Crohn's colitis, four having severe hyposplenism and four normal splenic function. The antibody response to phi X174 was grossly impaired in those with hyposplenism.
摘要
对8名炎症性肠病患者进行了测试，以检测他们对静脉注射颗粒抗原φX174产生血清学反应的能力。其中7名患者患有广泛性溃疡性结肠炎，1名患者患有广泛性克罗恩病，4名患者存在严重脾功能减退，4名患者脾功能正常。脾功能减退患者对φX174的抗体反应严重受损。
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