Vovin R Ia, Eryshev O F, Khvilivitskiĭ T Ia
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(3):397-402.
The authors studied the clinical picture of manic-depressive psychoses in 71 patients who had signs of an organic brain lesion (both anamnestically and clinically), which were confirmed by X-ray and EEG data. It was established that these patients more frequently exhibit atypical forms of affective conditions (anxious--depersonalizational syndromes, angry mania). As a rule, they also have a significant amount of supplementary psychopathological signs in the syndrome structure (dysphorea, obsessions, depersonalization). Such conditions quite often are refractory to therapy and require special therapeutical approaches.
作者研究了71例有器质性脑损害体征（病史和临床均有表现）患者的躁狂抑郁症临床表现，这些体征经X线和脑电图数据证实。结果发现，这些患者更常表现出情感状况的非典型形式（焦虑——人格解体综合征、愤怒躁狂）。通常，他们在综合征结构中也有大量补充性精神病理体征（运动障碍、强迫观念、人格解体）。这类情况往往对治疗难治，需要特殊的治疗方法。
