Lassus A
Curr Med Res Opin. 1981;7(6):370-3.
A total of 50 patients with moderately severe acne was treated with either 3%, 5% or 10% benzoyl peroxide gel for 4 weeks. Forty-eight patients maintained the treatment for the whole trial period while in 2 cases treatment has to be discontinued because of severe irritation of the treated skin areas. In all the remaining cases a definite remission of the acne activity could be observed at the end of the 4-weeks' trial. In some cases the gel had to changed to a stronger or a milder concentration during the trial either because of insufficient effectiveness or irritation.
共有50名中度严重痤疮患者接受了3%、5%或10%的过氧化苯甲酰凝胶治疗，为期4周。48名患者在整个试验期内持续接受治疗，而有2例因治疗皮肤区域出现严重刺激而不得不停止治疗。在所有其余病例中，在4周试验结束时可观察到痤疮活动明显缓解。在某些病例中，由于疗效不足或出现刺激，在试验期间不得不将凝胶更换为浓度更高或更低的产品。
