Local treatment of acne. A clinical study and evaluation of the effect of different concentrations of benzoyl peroxide gel.

A total of 50 patients with moderately severe acne was treated with either 3%, 5% or 10% benzoyl peroxide gel for 4 weeks. Forty-eight patients maintained the treatment for the whole trial period while in 2 cases treatment has to be discontinued because of severe irritation of the treated skin areas. In all the remaining cases a definite remission of the acne activity could be observed at the end of the 4-weeks' trial. In some cases the gel had to changed to a stronger or a milder concentration during the trial either because of insufficient effectiveness or irritation.