Bone scintigraphy in evaluation of Didronel therapy for Paget's disease.

A case of advanced Paget's disease was successfully treated with Didronel. All indicators of disease activity have been in remission for two years post-therapy. Although sequential radiographs obtained before and after treatment showed slight changes that might have reflected a reparative process, bone scintigraphs revealed more prominent changes, so that radionuclide bone imaging could well be considered as the follow-up imaging study of choice after treatment of Paget's disease.