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移植耐受的不同状态以及耐受的遗传问题。

Different states of transplantation tolerance, and the problem of inheritance of tolerance.

作者信息

Hasek M, Holán V, Kousalová M

出版信息

Immunol Lett. 1981 Aug;3(3):183-6. doi: 10.1016/0165-2478(81)90125-5.

Abstract

In agreement with previous results, we failed to observe hereditary transmission of transplantation tolerance in the progeny of tolerant male mice when tested by skin grafting. At the same time we showed that the detection of the tolerance state depended on the test of immunity used. The possibility has not excluded that positive results with hereditary transmission of tolerance via fathers [1-3] may be due to the appropriate detection systems.

摘要

与先前的结果一致,当通过皮肤移植进行测试时,我们未能在耐受雄性小鼠的后代中观察到移植耐受的遗传传递。同时,我们表明耐受状态的检测取决于所使用的免疫测试。通过父亲进行耐受遗传传递得到阳性结果[1-3]的可能性并未排除,这可能是由于适当的检测系统所致。

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