Godard F, King M, Guidoin R, Marois M, Garton A, Blais P, Gosselin C, Gunasekera K
J Mal Vasc. 1981;6(3):167-71.
A 56 year old patient fitted with a femoro-popliteal Dacron prosthesis (Weavenit-Meadox Medical) 84 months earlier, presented with a severe palpable dilation in the middle part of the graft. The dilated segment of the prosthesis was resected locally and spliced to a new fabric device. The explanted section of prosthesis was analyzed; the dilation was found to extend only over several centimeters near the centre of the prosthesis. The degree of "healing" was found to be satisfactory except in the part which was most distended; this area also revealed mild bacterial colonization. Physico-chemical analysis of the fabric revealed that the dilation had taken place subsequently to hydrolytic degradation of the polyester fibres. Manufacturing conditions may have contributed to predisposing parts of the prosthesis to accelerated biodeterioration in vivo.
一名56岁患者,84个月前植入了股腘动脉涤纶人工血管(Weavenit-Meadox Medical公司产品),现出现人工血管中部严重可触及的扩张。局部切除人工血管的扩张段,并拼接上新的织物装置。对切除的人工血管段进行分析;发现扩张仅在人工血管中心附近延伸数厘米。除了扩张最严重的部分,“愈合”程度令人满意;该区域还显示有轻度细菌定植。对织物的物理化学分析表明,扩张是在聚酯纤维水解降解之后发生的。制造条件可能促使人工血管的某些部分在体内加速生物降解。