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[主动脉根部收缩运动的血流动力学相关性]

[Hemodynamic correlation of the systolic movement of the aortic root].

作者信息

Fantini F, Barletta G A, Di Donato M, Bisi G, Malfanti P L

出版信息

G Ital Cardiol. 1981;11(3):345-50.

PMID:7286509
Abstract

Factors influencing the anterior systolic movement of the aortic posterior wall (PAM) are complex and still controversial. Left atrial events seem to be more important that stroke volume or left ventricular function in determining PAM. Even if the reduction of systolic aortic movement is generally associated to a severe impairment of left ventricular function, very few studies correlate the changes in the amplitude of aortic systolic movement to the hemodynamic pattern. In 50 patients posterior aortic wall echocardiograms, right heart catheterization and 99mTc angiocardiography were performed within 24 h. According to hemodynamic and left ventricular wall motion parameters 18 patients resulted to have a normal (1st group) and 32 patients (2nd group) an impaired left ventricular function. In the 2nd group mean values of PAM were significantly lower than in the 1st group (7.4 +/- 2.9 mm vs 10.2 +/- 1.9 mm). A significant correlation was found between PAM and hemodynamic parameters, i.e. CPW (r = 0.58), EF (r = 0.58) and SV (r = 0.40), whereas no significant correlations were found between these parameters and left atrial dimensions and between PAM and left atrial dimensions. A high significant correlation was found between PAM and echocardiographically measured septal wall motion (r = 0.80). All patients with PAM Less Than 6 mm and echo septal wall motion Less Than 5 mm had an akinesis or a dyskinesis of septal wall quantitatively determined with 99mTc angiocardiography. These findings suggest that one of the main determinants of PAM is left ventricular wall motion and in particular left ventricular septal motion.

摘要

影响主动脉后壁收缩期向前运动(PAM)的因素复杂且仍存在争议。在决定PAM方面,左心房事件似乎比心搏量或左心室功能更为重要。即使主动脉收缩期运动的减弱通常与左心室功能的严重受损相关,但很少有研究将主动脉收缩期运动幅度的变化与血流动力学模式联系起来。对50例患者在24小时内进行了主动脉后壁超声心动图、右心导管检查和99mTc血管造影。根据血流动力学和左心室壁运动参数,18例患者左心室功能正常(第1组),32例患者(第2组)左心室功能受损。第2组PAM的平均值显著低于第1组(7.4±2.9mm对10.2±1.9mm)。发现PAM与血流动力学参数即肺毛细血管楔压(r = 0.58)、射血分数(r = 0.58)和心搏量(r = 0.40)之间存在显著相关性,而这些参数与左心房大小之间以及PAM与左心房大小之间未发现显著相关性。发现PAM与超声心动图测量的室间隔壁运动之间存在高度显著相关性(r = 0.80)。所有PAM小于6mm且超声室间隔壁运动小于5mm的患者,经99mTc血管造影定量测定显示室间隔壁运动减弱或运动障碍。这些发现表明,PAM的主要决定因素之一是左心室壁运动,尤其是左心室室间隔运动。

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