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[采用三组分淋巴细胞混合培养法检测肿瘤患者血液中的抑制性淋巴细胞]

[Detection of suppressor lymphocytes in the blood of oncological patients by using a 3-component lymphocyte mixed culture].

作者信息

Govallo V I

出版信息

Vopr Onkol. 1981;27(9):30-6.

PMID:6457445
Abstract

A 3 component mixed lymphocyte culture was used to identify the suppressor cell activity of lymphocytes in the blood of patients suffering from osteogenic sarcoma, osteoblastoclastoma and lung tumor. The lymphocytes of these patients suppressed the blastogenic reaction of lymphocytes from two unrelated donors. The suppressive activity of the lymphocytes form the patients with bone sarcoma was the strongest. In most cases, a direct correlation was found between the suppressive activities of lymphocytes and serum from the same patients.

摘要

采用三组分混合淋巴细胞培养法,以鉴定骨肉瘤、成骨细胞瘤和肺癌患者血液中淋巴细胞的抑制细胞活性。这些患者的淋巴细胞抑制了来自两名无关供体的淋巴细胞的增殖反应。骨肉瘤患者淋巴细胞的抑制活性最强。在大多数情况下,发现同一患者的淋巴细胞和血清的抑制活性之间存在直接相关性。

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