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[患者淋巴细胞对自体活肿瘤细胞的体外免疫反应]

[In vitro immune response of patient lymphocytes to live autologous tumor cells].

作者信息

Grigor'eva M P, Kosmiadi G A, Govallo V I

出版信息

Vopr Onkol. 1980;26(9):8-11.

PMID:7423909
Abstract

In 87% of patients with malignant tumors and in 24% of patients with benign tumors there was found the in vitro immune response of lymphocytes to autologous tumor cells. Most of the autologous sera influenced the immune lymphocytes: those of malignant tumor patients usually blocked while those of benign tumor patients stimulated the immune reaction. Both the blocking and stimulating serum activities could be removed by absorption of the sera with living autologous tumor cells. Following the absorption intact sera of some patients with malignant tumors obtained the blocking capacity.

摘要

在87%的恶性肿瘤患者和24%的良性肿瘤患者中发现淋巴细胞对自体肿瘤细胞的体外免疫反应。大多数自体血清影响免疫淋巴细胞:恶性肿瘤患者的血清通常起阻断作用,而良性肿瘤患者的血清则刺激免疫反应。通过用活的自体肿瘤细胞吸收血清,可去除阻断和刺激血清活性。吸收后,一些恶性肿瘤患者的完整血清获得了阻断能力。

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