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本文引用的文献

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The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes.人红细胞无血红蛋白空泡的制备及其化学特性
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Contact-mediated changes in the fluidity of membrane lipids in normal and malignant transformed mammalian fibroblasts.正常和恶性转化的哺乳动物成纤维细胞中膜脂流动性的接触介导变化。
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Fluorescence-polarization measurements on normal and mutant human skin fibroblasts.对正常和突变型人类皮肤成纤维细胞进行荧光偏振测量。
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A convenient and sensitive fluorescence assay for phospholipid vesicles using diphenylhexatriene.一种使用二苯基己三烯对磷脂囊泡进行简便且灵敏的荧光测定法。
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Translocation of a fluorescent lipid probe between contacting cells: evidence for membrane lipid interactions.荧光脂质探针在接触细胞间的转位:膜脂相互作用的证据
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亨廷顿舞蹈症患者外周细胞的膜流动性测量

Membrane fluidity measurements in peripheral cells from Huntington's disease patients.

作者信息

Beverstock G C, Pearson P L

出版信息

J Neurol Neurosurg Psychiatry. 1981 Aug;44(8):684-9. doi: 10.1136/jnnp.44.8.684.

DOI:10.1136/jnnp.44.8.684
PMID:6457900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC491088/
Abstract

The primary gene defect of Huntington's disease is believed to involve the membrane of some peripheral cells. The membrane fluidity of skin fibroblasts, erythrocytes and leucocytes was measured by fluorescence polarisation of a lipid specific probe, 1,6 diphenyl, 1,3,5 hexatriene. No significant difference between controls and Huntington's disease patients could be demonstrated.

摘要

亨廷顿舞蹈病的主要基因缺陷被认为与某些外周细胞的细胞膜有关。通过脂质特异性探针1,6-二苯基-1,3,5-己三烯的荧光偏振来测量皮肤成纤维细胞、红细胞和白细胞的膜流动性。未发现对照组与亨廷顿舞蹈病患者之间存在显著差异。